Lyophilized powder
What is lyophilized powder? Lyophilization is the term used for the freeze drying process that results in the powder found inside of the peptide vials. These powders can range in appearance from a white powdery substance to a solid “puck” appearance and can have different colors from the standard white found in most peptides to a blue powder in peptides containing GHK-Cu and an orange powder in 5-Amino-1MQ. There is a wide variation of presentations that lyophilized powder can present as and these variations are not a reflection of purity or potency and are within the normal range.
Lyophilization creates a stable peptide product with an extended shelf life. Lyophilized peptides are resistant to changes in temperature and preserves the peptides for long term storage. Prior to use, lyophilized peptides must be reconstituted.
Reconstitution
Most peptides are reconstituted with Bacteriostatic water. Bacteriostatic water is a sterile water product that contains benzyl alcohol, usually at 0.9%, as a preservative that inhibits the growth of bacteria inside of the reconstituted peptides.
Special reconstitution solvents
Certain peptides, such as AOD-9604 requires the use of an addition solvent. AOD-9604 has the tendency to form a gel upon reconstitution, in order to prevent this gelling, it is common to add Acetic Acid to the peptide and bacteriostatic water solution, typically in a 5:1 BAC water to Acetic Acid ratio. An example of this would be 0.8ml BAC water and 0.2ml Acetic Acid resulting in 1ml of solution.
Syringes
The reconstitution of peptides can be achieved with any size needle and syringe. We recommend using the smallest needle possible, to prevent creating large holes in your multi-use Bacteriostatic water and peptide vials. In peptides that require 1ml of Bacteriostatic water, it is simple and common to use a 1ml insulin syringe for reconstitution. For peptides that require more than 1ml Bacteriostatic water, it may make more sense to use a larger syringe such as a 3ml, 5ml or even larger depending on the amount of Bacteriostatic water you are adding to the vial.
Administration of peptides is typically done with a 0.3ml, 0.5ml or 1ml insulin syringe.
Mixing Peptides
Do not mix peptides in the syringe, unless they are premixed in the vial or you are using a combination of peptides that are commonly found pre-mixed in a vial, such as CJC-1295 / Ipamorelin and BPC-157 / TB-500. These products are known to be stable and not interfere and disrupt the delicate peptide bonds that hold these compounds together. Mixing peptides that may react to one another can destroy peptide bonds and reduce the potency and effectiveness of the peptides that were mixed together.
Storage
Reconstituted peptides must be stored in a refrigerator to prevent degradation. Lyophilized peptides may be stored at room temperature for a short period of time, but should be stored in a refrigerator when possible. For longer periods of storage, lyophilized peptides should be stored in a freezer.
Typically, lyophilized peptides are able to be transported in normal weather conditions without degradation in purity or potency.
